After following the development of bioterrorism around the world, he joins a new organization and goes to Africa, where the latest threat has emerged. Chris Redfield is joined by a new partner, Sheva Alomar, who contributes with strength, intelligence and sniping. To survive, Chris and Sheva must work together to meet the various challenges they face and discover the truth behind the threats of Bioterrorism.

Co-producers and series veterans June Takeuchi (Lost Planet) and Masachicka Kawata (Resident Evil 4 Wii Edition Resident Evil: The Umbrella Chronicles) have developed Resident Evil 5 for the next generation of consoles. Resident Evil 5 is the sequel to one of the highest rated video games in history, according to Metacritic.com and Gamerankings.com.